Book Chapters

  • “The growing influence of nanotechnology in our lives”, A. Ranzoni and M.A. Cooper, in “Micro and nanotechnology for vaccine development”, Eds. M Skwarczynski and I Toth, 2016, William Andrew, ISBN: 9780323400299
  • "Label-free technologies - Which technique to use and what to watch out for ” in " Label-free Biosensor Methods in Drug Discovery." Ed. Y. Fang, Springer Methods in Pharmacology & Toxicology Series 2015, ISBN: 978-1-4939-2616-9.

  • Sensor surfaces and receptor deposition” in "Label-free Biosensors: Techniques and Applications" Ed. M.A. Cooper, Cambridge University Press, 2009,
    ISBN-13: 9780521711517.

  • Interactions with membranes and membrane receptors” in "Label-free Biosensors: Techniques and Applications" Ed. M.A. Cooper, Cambridge University Press, 2009,
    ISBN-13: 9780521711517.

  • Resonant Acoustic Profiling and Rupture Event Scanning” in "Piezoelectric Sensors", Vol. 5, 2006, Springer Verlag, Eds. Steinem C., Janshoff A., (part of the book series “Chemical Sensor and Biosensors, Series Ed. Otto S. Wolfbeis).


Journal Articles


  1. “Old dogs and new tricks in antimicrobial discovery”, Mark S. Butler, Mark A. T. Blaskovich, Jeremy G. Owen and Matthew A. Cooper, Current Opinion in Microbiology, Accepted May 2016
  2. “Antibiotics in the Clinical Pipeline at the End of 2015”, Mark S. Butler, Mark A. T. Blaskovich and Matthew A. Cooper, Journal of Antibiotics, Accepted May 2016
  3. "An ‘unlikely’ pair: The antimicrobial synergy of polymyxin B in combination with the cystic fibrosis trans-membrane conductance regulator drugs KALYDECO and ORKAMBI", Schneider, Elena; Azad, Mohammad; Han, Mei-Ling; Zhou, Qi; Wang, Jiping; Huang, Johnny; Cooper, Matthew; Doi, Yohei; Baker, Mark; Bergen, Philip; Muller, Mark; Li, Jian; Velkov, Tony, ACS Infectious Diseases, 2016, DOI: 10.1021/acsinfecdis.6b00035
  4. "The selective NLRP3-inflammasome inhibitor MCC950 reduces infarct size and preserves cardiac function in a pig model of myocardial infarction", European Heart Journal, Accepted April 2016
  5. “The ER-Mitochondria tether ERMES orchestrates fungal immune evasion, illuminating inflammasome responses to hyphal signals", Timothy Tucey, Jiyoti Verma-Gaur, Julie Nguyen, Victoria Hewitt, Tricia Lo, Miguel Shingu-Vazquez, Avril Robertson, James Hill, Filomena Pettolino, Travis Beddoe, Matthew Cooper, Thomas Naderer, and Ana Traven, mSphere - American Society for Microbiology, Accepted April 2016
  6. “Nitroimidazole carboxamides as antiparasitic agents targeting Giardia lamblia, Entamoeba histolytica and Trichomonas vaginalis”, Angie M. Jarrad, Anjan Debnath, Yuki Miyamoto, Karl Hansford, Ruby Pelingon, Mark S. Butler, T. Bains, Tommy Karoli, Mark. A. Blaskovich, Lars Eckmann, Matthew A Cooper, European Journal of Medicinal Chemistry, 2016, DOI: 10.1016/j.ejmech.2016.04.064
  7. “Contribution of amphipathicity and hydrophobicity to the antimicrobial activity and cytotoxicity of β-hairpin peptides”,  Ingrid A Edwards, Alysha G. Elliott, Angela M. Kavanagh, Johannes Zuegg, Mark A. T. Blaskovich and Matthew A. Cooper, ACS Infectious Diseases, 2016, DOI: 10.1021/acsinfecdis.6b00045
  8. “Discovery of functionally selective C5aR2 ligands: novel modulators of C5a signalling activity in vitro and in vivo”, Daniel E. Croker, Peter N. Monk, Reena Halai, Geraldine Kaeslin, Zoe Schofield, Mike C. L. Wu, Richard J. Clark, Mark A. T. Blaskovich, Dimitrios Morikis, Christodoulos A. Floudas, Matthew A. Cooper and Trent M. Woodruff, The Journal of Immunology & Cell Biology, 2016, DOI: 10.1038/icb.2016.43
  9. "Complete Genome Sequence of the Klebsiella quasipneumoniae subsp. similipneumoniae Strain ATCC 700603", Alysha Elliott, Devika Ganesamoorthy, Lachlan Coin, Matthew Cooper, and Minh Duc Cao, Genome Announcements – Prokaryotes, Accepted April 2016
  10. “Platinum-based anticancer drugs encapsulated liposome and polymeric micelle formulation in clinical trials”, Zhou Hang, Mathew A. Cooper, Zyta M. Ziora, Biochemical Compounds, 2016, 4 (2) DOI:10.7243/2052-9341-4-2
  11. “Chemical philanthropy - a path forward for antibiotic discover?" Karl A. Hansford, Mark A.T. Blaskovich, Matthew A Cooper, Future Medicinal Chemistry, Accepted March 2016
  12. “Short cationic lipopeptides as effective antibacterial agents: design, physicochemical properties and biological evaluation”, Azmi F, Elliott A. G, Marasini N, Ramu S, Ziora Z. M, Kavanagh A. M, Blaskovich M. A. T, Cooper M. A, Skwarczynski M, Toth I, Bioorganic & Medicinal Chemistry, 2016, DOI: 10.1016/j.bmc.2016.03.053
  13. "A generic screening platform for inhibitors of virus induced cell fusion using cellular electrical impedance" by Daniel Watterson, Jodie Rbinson, Keith Chappell, Mark Butler, David Edwards, Scott Fry, Imogen Bermingham, Matthew Cooper, and Paul Young, Scientific Reports, 2016, 6:22791, DOI: 10.1038/srep22791
  14. “Antibacterial Low Molecular Weight Cationic Polymers: Dissecting the Contribution of Hydrophobicity, Chain Length and Charge to Activity”, James L. Grace, Nghia P. Truong, John F. Quinn, Johnny Huang, Matthew Cooper, Soon-Ea Cheah , Jian Li, Tony Velkov, Thomas P. Davis, Michael R. Whittaker, RSC Advances, 2016, DOI: 10.1039/C5RA24361K
  15. “Human Monocytes Engage an Alternative Inflammasome Pathway”, Moritz M. Gaidt, Thomas S. Ebert, Dhruv Chauhan, Tobias Schmidt, Jonathan L. Schmid-Burgk, Francesca Rapino, Avril A. B. Robertson, Matthew A. Cooper and Veit Hornung; Immunity, 2016,
    DOI: 10.1016/j.immuni.2016.01.012
  16. “Activity and Predicted Nephrotoxicity of Synthetic Antibiotics Based on Polymyxin B", Gallardo-Godoy, Alejandra; Muldoon, Craig; Becker, Bernd; Elliott, Alysha; Lash, Lawrence; Huang, Johnny; Butler, Mark; Pelingon, Ruby; Kavanagh, Angela; Ramu, Soumya; Phetsang, Wanida; Blaskovich, Mark; Cooper, Matthew, Journal of Medicinal Chemistry, 2016, DOI: 10.1021/acs.jmedchem.5b01593



  1. “A community-based approach to new antibiotic discovery”, Matthew A Cooper, Nature Reviews Drug Discovery, 2015, 14 (9), 587–588, DOI: 10.1038/nrd4706
  2. “Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity” J. Zuegg , C. Muldoon, G. Adamson, D. McKeveney, G.L. Thanh, R. Premraj, B. Becker, M. Cheng, A. Elliott , J. Huang, M.S. Butler, M. Bajaj, J. Seifert, L. Singh, N. Galley, D. Roper, A. Lloyd, C. Dowson, T.-J. Cheng, W.-C. Cheng, D. Demon, E. Meyer, W. Meutermans  and M.A. Cooper. Nature Communications, 2015, 6:7719, DOI: 10.1038/ncomms8719
  3. “A small molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases,” R.C. Coll, A.A.B. Robertson, J.J. Chae, S.C.. Higgins, R. Muñoz-Planillo, M.C.. Inserra, I. Vetter, L.S.. Dungan, B.G.. Monks, A. Stutz, D.E. Croker, M.S. Butler, M. Haneklaus, C.E. Sutton, G. Núñez, E. Latz, D.L. Kastner, K.H.G. Mills, S.L. Masters, K. Schroder, MA Cooper, L.A.J. O’Neill, Nature Medicine, 2015, 21, 248-255,
    DOI: 10.1038/NM.3806
  4. “Antibacterial and antifungal screening of natural products sourced from Australian fungi and characterisation of pestalactams D–F”, Karren D. Beattie, Nicola Ellwood, Rohitesh Kumar, Xinzhou Yang, Peter C. Healy, Vanida Choomuenwai, Ronald J. Quinn, Alysha G. Elliott, Johnny X. Huang, Jessica L. Chitty, James A. Fraser, Matthew A. Cooper, Rohan A. Davis, Phytochemistry,2015, 124, 79-85, DOI: 10.1016/j.phytochem.2015.12.014
  5. “The Effect of Novel Compound MCC950 on the NLRP3 Inflammasome in the RA Joint”,  T. McGarry, A.A. Robertson, C. Orr, R.C. Coll, M.A. Cooper, L.A. O'Neill, D.J. Veale and U. Fearon, Annals of the Rheumatic Diseases, 2015, 74(suppl 2), 202 2-202, DOI: 10.1136/annrheumdis-2015-eular.3985
  6. “Activation of redox-sensitive inflammasomes underlies the biological phenotype of myelodysplastic syndromes”, A. Basiorka, K. Mcgraw, E. Eksioglu, X. Chen, J. Johnson, E. Padron, R. Komrokji, L. Sokol, R, Coll, L. O'Neill, M. Cooper, A. Robertson, S. Wei, A. List, Leukemia Research, 2015, 32, S14, DOI: 10.1016/S0145-2126(15)30033-3
  7. “Realtime analysis and visualisation of MinION sequencing data with npReader”, Minh Duc Cao, Devika Ganesamoorthy, Matthew A. Cooper and Lachlan J. M. Coin, Bioinformatics, 2015, DOI: 10.1093/bioinformatics/btv658
  8. “An optimized whole blood assay measuring expression and activity of NLRP3-, NLRC4 and AIM2-inflammasomes”, L Grinstein, H Luksch, AAB Robertson, MA Cooper, S Winkler, & A Rösen-Wolff, Pediatr Rheumatol Online J., 2015, 13(Suppl 1): O51,
    DOI: 10.1186/1546-0096-13-S1-O51
  9. “Clostridium difficile infection: current and emerging therapeutics”, Angie M. Jarrad, Mark A. T. Blaskovich, Dena Lyras, Matthew A. Cooper, Current Treatment Options in Infectious Diseases, 2015, 7 (4) 317-334, DOI: 10.1007/s40506-015-0062-4
  10. "Quantification of NS1 dengue biomarker in serum via optomagnetic nanocluster detection", Paula Antunes, Daniel Watterson, Mattias Parmvi, Robert Burger, Anja Boisen, Paul Young, Matthew A. Cooper, Mikkel F. Hansen, Andrea Ranzoni & Marco Donolato, Scientific Reports, 2015, 5 (16145) 1-10, DOI: 10.1038/srep16145
  11. “Inflammasomes in COPD and neutrophilic asthma”, Richard Y Kim, James W Pinkerton, Peter G Gibson, Matthew A. Cooper, Jay C Horvat, Philip M Hansbro, Thorax, 2015, 70 (12), 1199-1201, DOI: 10.1136/thoraxjnl-2014-206736
  12. “Metronidazole-triazole conjugates: activity against Clostridium difficile and parasites”, Jarrad, Angie M., Karoli, Tomislav, Anjan, Debnath, Tay, Chin Yen, Huang, Johnny X., Kaeslin, Geraldine, Elliott, Alysha G., Miyamoto, Yukiko, Ramu, Soumya, Kavanagh, Angela M., Zuegg, Johannes, Eckmann, Lars, Blaskovich, Mark A. and Cooper, Matthew A., European Journal of Medicinal Chemistry, 2015, 101, 96-102,
    DOI: 10.1016/j.ejmech.2015.06.019
  13.  “Shaping Nanoparticles with Hydrophilic Compositions and Hydrophobic Properties as Nanocarriers for Antibiotic Delivery”, Yusilawati Ahmad Nor, Yuting Niu, Surajit Karmakar, Liang Zhou, Chun Xu, Jun Zhang, Hongwei Zhang, Meihua Yu, Donna Mahony, Neena Mitter, Matthew A. Cooper, and Chengzhong Yu, ACS Cent. Sci., 2015,
    DOI: 10.1021/acscentsci.5b00199
  14. “Self-assembling lipopeptides with a potent activity against Gram-positive bacteria, including multidrug resistant strains”, Fazren Azmi, Alysha G Elliott, Zeinab G Khalil, Waleed M Hussein Angela Kavanagh, Johnny X Huang, Michelle Quezada, Mark A T Blaskovich, Robert J Capon, Matthew A Cooper, Mariusz Skwarczynski1, Istvan Toth, Nanomedicine, 2015, DOI: 10.2217/nnm.15.137
  15. “Flemingin-Type prenylated chalcones from the Sarawak rainforest plant Desmodium congestum”, K.A. Rees, C. Bermudez, D.J. Edwards, AG. Elliott, J.E. Ripen, C. Seta, J.X. Huang, M.A. Cooper, J.A. Fraser, T.C. Yeo and M.S. Butler, J.Nat. Prod., 2015, 2141–2144,
    DOI: 10.1021/acs.jnatprod.5b00410
  16. “NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5”, Paul J. Baker, Dave Boucher, Damien Bierschenk, Christina Tebartz, Paul G. Whitney, Damian B. D'Silva, Maria C. Tanzer, Mercedes Monteleone, Avril A. B. Robertson, Matthew A. Cooper, Silvia Alvarez-Diaz, Marco J. Herold, Sammy Bedoui, Kate Schroder and Seth L. Masters, 2015, European Journal of Immunology, 45 (10), 2918 – 2926, DOI: 10.1002/eji.201545655
  17. “Mucin binding reduces colistin antimicrobial activity”, J.X. Huang, M.A.T. Blaskovich, R. Pelingon, S. Ramu A. Kavanagh, A.G. Elliott, M.S. Butler, A.B. Montgomery & M.A. Cooper. Antimicrobial Agents and Chemotherapy, 2015, 6, 11, DOI: 10.1128/AAC.00808-15
  18. “Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt-induced hypertension in mice”, S.M. Krishnan, J.K. Dowling, Y.H. Ling, H. Diep, C.T. Chan, D. Ferens, M.M. Kett, A. Pinar, C.S. Samuel, A. Vinh, T.V. Arumugam, T.D. Hewitson, B.K. Kemp-Harper, A.A.B. Roberston, M.A. Cooper, E. Latz, A. Mansell, C.G. Sobey, G.R. Drummond. British J. Pharmacol., 2015, 14, DOI: 10.1111/bph.13230
  19. “Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli”, Kolja Schaale, Kate M. Peters, Anna K. Fritzsche, Minh-Duy Phan, Makrina Totsika, Avril A.B. Robertson, Katie B. Nichols, Matthew A. Cooper, Glen C. Ulett, Katryn J. Stacey, Kate Schroder, Mark A. Schembri, Matthew J Sweet. Mucosal Immunology, 2015, 9 (1), 124-136, DOI: 10.1038/mi.2015.44
  20. “Molecular  characterization of the hemagglutinin glycan-binding specificity of egg-adapted vaccine strains of the pandemic 2009 H1N1 swine influenza A virus”, Vince Carbone, Elena K. Schneider, Steve Rockman, Mark Baker, Johnny Huang, Matthew Cooper, Chi Ong, Elizabeth Yuriev, Paul Ramsland, Jian Li, Tony Velkov, Molecules, 2015,  20 (6), 10415-10434, DOI: 10.3390/molecules200610415
  21. “Improved Immunoassay Sensitivity in Serum as a Result of Polymer- Entrapped Quantum Dots: ‘Papaya Particles” A. Razoni, A. den Hamer, T. Karoli, J. Buechler & M.A. Cooper, Anal. Chem., 2015, 87 (12), 6150 – 6157, DOI: 10.1021/acs.analchem.5b00762
  22. “Synergistic killing of NDM-producing MDR Klebsiella pneumoniae by two ‘old’ antibiotics—polymyxin B and chloramphenicol”, Nusaibah Abdul Rahim, Soon-Ee Cheah, Matthew D. Johnson, Heidi Yu, Hanna E. Sidjabat, John Boyce, Mark Butler, Matthew Cooper, Jing Fu, David L. Paterson, Roger L. Nation, Phillip J. Bergen, Tony Velkov, Jian Li, JAC, 28 May 2015, 70 (9), 2589-2597, DOI: 10.1093/jac/dkv135
  23. “Helping chemists discover new antibiotics”, M.A.T. Blaskovich, J. Zuegg, A.G. Elliott & M.A. Cooper, ACS Infectious Diseases, 2015, 1(7), 3, DOI: 10.1021/acsinfecdis.5b00044
  24. “Synthesis and evaluation of cationic norbornanes as peptidomimetic antibacterial agents”, S.M. Hickey, T.D. Ashton, S.K. Khosa, R.N. Robson, J.M. White, J. Li, R.L. Nation, H.Y. Yu, A.G. Elliott, M.S. Butler, J.X. Huang, M.A. Cooper & F.M. Pfeffer, Org. Biomol. Chem., 2015, 13 (22), 6225-41, DOI: 10.1039/C5OB00621J
  25. “Ethanol concentration influences the mechanisms of wine tannin interactions with poly(L-proline) in model wine”. J. McRae, Z.M. Ziora, S. Kassara, M.A. Cooper, P. Smith. J. Agric. & Food Chem., 2015, 63 (17), 4345-4352, DOI: 10.1021/acs.jafc.5b00758
  26. “Urinary Biomarkers for Detection of Early and Advanced Chronic Kidney Disease-A Pilot Study”, Vlasta Korenkova, Alun Jones, Wendy E Hoy, Christudas Morais, Matthew A Cooper, Glenda C Gobe, Medicinal Chemistry, 2015, 5:096-103,
    DOI: 10.4172/2161-0444.1000249
  27. “Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human proximal tubular cells”, J. X. Huang, G. Kaeslin, M.V. Ranall, M.A. Blaskovich, B. Becker, M. S. Butler, M.H. Little, L. Lash & M.A. Cooper, Pharmacology Research & Perspectives, 2015, 3 (3), 14,DOI: 10.1002/prp2.148
  28. “Synthesis of norbornane bisether antibiotics via silver-mediated alkylation”, S.M. Hickey, T.D. Ashton, J.M. White, J. Li, R.L. Nation, H.Y. Yu, A.G. Elliott, M.S. Butler, J.X. Huang, M.A. Cooper & F.M. Pfeffer, RSC Advances, 2015, 5 (36), 28582-28596,
    DOI: 10.1039/C5RA03321G
  29. “The C. difficile treatment pipeline: challenges in discovery and development of new agents” A. Jarrad, T. Karoli, M.A. Blaskovich, D. Lyras & M.A. Cooper. J. Med. Chem., 2015, 58 (13), 5164 – 5185, DOI: 10.1021/jm5016846
  30. “QCM-based rapid analysis of DNA” F.N. Dultsev, E.A. Kolosovsky, M.A. Cooper, A.A. Lomzov, D.V. Pyshnyi, Sens. Biosens. Res., 2015, 4, 11-15,
  31. “α-Conotoxin dendrimers have enhanced potency and selectivity for nicotinic acetylcholine receptors”, J. Wan, J.X. Huang, I. Vetter, M. Mobli, J. Lawson, H.S. Tae, N. Abraham, P. Blessy, M.A. Cooper, D. Adams, R. Lewis & P. Alewood, J. Am Chem Soc., 2015, 137 (9), 3209-3212, DOI: 10.1021/jacs.5b00244
  32. “A new antibiotic with potent activity against Gram-positive bacteria targets MscL”. I. Iscla, R. Wray, P. Blount, J. Larkins-Ford, A.L. Conery, F.M. Ausubel, S. Ramu, A. Kavanagh, J.X. Huang, M.A. Blaskovich, M.A. Cooper, A. Obregon-Henao, I Orme, E.S. Tjandra, U. Stroeher, M. Brown, C. Macardle, N. van Holst, C.L. Tong, A.D. Slattery, C.T. Gibon, C.L. Raston & R.A. Boulos. J. Antibiotics, 2015, 68, 453-462, DOI: 10.1038/ja.2015.4
  33. “Discovery of novel Pneumococcal surface antigen A (PsaA) inhibitors using a fragment-based drug design approach”, M. Bajaj, S. Mamidyala,, J. Zuegg, S. Begg, M. Ween, J.X. Huang, A. McEwan, B. Kobe, J. Pton, C. McDevitt & M.A. Cooper, ACS Chemical Biology, 2015, 10 (6), DOI: 10.1021/cb501032x
  34. “Facile synthesis of mono- and bis-methylated Fmoc-Dap, -Dab and –Orn building blocks”, F. Lindahl, H. Huang, D.P.Fairlie & M.A. Cooper, Chem. Comms., 2015, 51, 4496-4498 Advance Article,  51, 4496-4498, DOI: 10.1039/C4CC09780G
  35. “Drug-drug plasma protein binding interactions of ivacaftor”, E. Schneider, J. Huang, V. Carbone, M. Baker, J. Striessnig, M. Azad, M.A. Cooper, J. Li. J. Molec. Recog., 2015, 28 (6), 339-348, DOI: 101002/jmr.2447
  36. “Affinities and in-plane stress forces between glycopeptide antibiotics and biomimetic bacterial membranes.” S. Bi, A. Ranzoni, J.X. Huang, K. Hansford & M.A. Cooper, Sensing and Bio-Sensing Research, 2015, 3, 24-30, DOI: 10.1016/j.sbsr.2014.10.003
  37. “Evaluation of direct and multi-layer passivation and capture chemistries for nanoparticle-based biosensor applications.” S. KC, A. Ranzoni & M.A. Cooper, Biosensors & Bioelectronics. 2015, 67, 769-774, DOI: 10.1016/j.bios.2014.09.048



  1. “Cell- and biomarker-based assays for predicting nephrotoxicity”. J. Huang, M.A. Blaskovich &  M.A. Cooper. Expert Opinion on Drug Metabolism & Toxicology. 2014, 10 (12) 1621-1635 DOI: 10.1517/17425255.2014.967681
  2. “Ramoplanin at bacterial concentrations induces bacterial membrane depolarization in Staphylococcus aureus”, M. Cheng, J.X. Huang, S. Ramu, M.S. Butler and M.A. Cooper, Antimicrob Agents and Chemo. 2014, 58(11) 6819-6827, DOI: 10.1128/AAC.00061-14
  3. “Derivations of ligands for the complement C3a receptor from the C-terminus of C5a”, R. Halai, M.L. Bellows-Petersen, W. Branchett, J. Smadbeck, C.A. Kieslich, D.E. Croker, M.A. Cooper, D. Morikis, T.M. Woodruff, C.A. Floudas & P.A. Monk. European J Pharmacol. 2014, 745, 15 Dec, 176-181, DOI: 10.1016/j.ejphar.2014.10.041
  4. “Natural product and natural product derived drugs in clinical trials”. M.S. Butler, A.A.B. Robertson & M.A. Cooper. Natural Product Reports. 2014, 31, 1612 – 1661,
    DOI: 10.1039/C4NP00064A
  5. “Glycopeptide Antibiotics: Back to the Future”, M.S. Butler, K.A. Hansford, M.A. Blaskovich & M.A. Cooper, Journal of Antibiotics 2014, 67, 631-644, DOI: 10.1038/ja.2014.111
  6. “Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destruction”,  C.J. Greenhill, G.W. Jones, M.A. Nowell, A.K. Harvey, A.N. Moiden, F.L. Collins, A.C. Bloom, R.C. Coll, A.B. Robertson, M.A. Cooper, M. Rosas, P.R. Taylor, L.A. O’Neill, I.R. Humphreys, A.S. Williams & S.R. Jones. Arthritis Research & Therapy, 2014, 16, 419 - 428, DOI: 10.1186/s13075-014-0419-y
  7. “An azido-oxazolidinone antibiotic for live bacterial cell imaging and generation of antibiotic variants” W. Phetsang, M.A. Blaskovich & M.A. Cooper Biorg Med Chem. 2014, 22, 4490-4498, DOI: 10.1016/j.bmc.2014.05.054
  8. “Pathway-selective antagonism of proteinase activated receptor 2”. J.Y. Suen, A. Cotterell, R.-J. Lohman, J. Lim, A. Han, M.-K. Yau, L. Liu, M.A. Cooper, D.A. Vesey, & D.P. Fairlie.  Brit. J. Pharmacol. 2014, 171 (17), 4112-4124, DOI: 10.1111/bph.12757
  9. “C5a2 can modulate ERK1/2 signaling in macrophages via heteromer formation with C5a1 and b-arrestin recruitment”, D.E. Croker, R. Halai, G. Kaeslin, E. Wende, B. Fehlhaber, A. Klos, P. Monk & M.A. Cooper. Immunol. Cell Biol. 2014, (92), 631-639,
    DOI: 10.1038/icb.2014.32
  10. “Surface stress sensors for rapid and ultrasensitive detection of active free drugs in human serum”,  J.W. Ndieyira, N. Kappeler, S. Logan, M.A. Cooper, C. Abell, R.A. McKendry & G. Aeppli, Nature Nanotechnology. 2014, 9, 225 - 232. DOI: 10.1038/nnano.2014.33
  11. “Monoacetylation of carbohydrate diols via trans-esterification with ethyl acetate” X. Lu, B. Becker & M.A. Cooper, Australian Journal of Chemistry. 2014, 67, 679-683,
    DOI:  10.1071/CH12518
  12. “Anti-cooperative ligand binding and dimerization in the glycopeptide antibiotic dalbavancin”, M. Cheng, Z. Ziora, K. Hansford, M.A. Blaskovich, M.S. Butler & M.A. Cooper. Organic & Biomol. Chem. 2014, 12 (16), 2568-2575, DOI: 10.1039/c3ob42428f
  13. “Natural product libraries: assembly, maintenance and screening”, M.S. Butler, F.R. Fontaine & M.A. Cooper. Planta Medica. 2014, 80, 1161-1170, DOI: 10.1039/C4NP00064A
  14. “Imperfect coordination chemistry facilititates metal ion release in the Psa permease”, R. M. Counago, M.P. Ween, S.L. Begg, M. Bajaj, J. Zuegg, M.L. O’Mara, M.A. Cooper, A.G. McEwan, J.C. Paton, B. Kobe, and C.A. McDevitt, Nature Chem Biol, 2014; 10, 35-41,
    DOI: 10.1038/nchembio.1382



  1. “Fine tuning the disassembly time of thermoresponsive polymer nanoparticles”. Nguyen T.D. Tran, Z. Jia, N.T. Phuoc, M.A.Cooper, M.J. Monteiro. Biomacromol., 2013, 14(10): 3463-471, DOI: 10.1021/bm4007858
  2. "C5a, but not C5a-des Arg induces upregulation of heteromer formation between its complement C5a receptors C5aR and C5L2”, D.E. Croker, R. Halai, D.P. Fairlie, M.A. Cooper. Immunol & Cell Biol., 2013, 91(10): 625-33, DOI: 10.1038/icb.2013.48
  3. "Neutrophils: a key component of ischemia reperfusion injury”, Z.V. Schofield, T.M. Woodruff, R. Halai, M. C-L Wu, M.A. Cooper. Shock, 2013, 40 (6): 463-70,
    DOI: 10.1097/SHK.0000000000000044
  4. “Nanoparticle sample preparation and mass spectrometry for rapid diagnosis of microbial infections” A. Ranzoni, H. Sidjabat and M.A. Cooper. Microbiology Australia, 2013, 34 (4), 170-174, DOI: 10.1071/MA13057
  5. “Probing the reactivity of o-phthalaldehydic acid/methyl ester: synthesis of N-isoindolinones and 3-arylaminophthalides”. S.K. Mamidyala and M.A. Cooper. Chem. Comm. 2013, 49(75): 8407-409, DOI: 10.1039/C3CC43838D
  6. “Antibiotics in the clinical pipeline in 2013”, M.S. Butler, M.A. Blaskovich and M.A. Cooper,
    J. Antibiot., 2013,  66(10): 571-91, DOI: 10.1038/ja.2013.86
  7. “In vivo evolution of antimicrobial resistance in a series of Staphylococcus aureus patient isolates: the entire picture or a cautionary tale?” S.J. van Hal, J.A. Steen, B.A. Espedido, S.M.Grimmond, M.A. Cooper, M.T.G. Holden, S.D. Bentley, I.B. Gosbell & S.O. Jensen. Journal of Antimicrobial Chemotherapy. 2013, 69(2): 363-67, DOI: 10.1093/jac/dkt354
  8. “Comparison of surface plasmon resonance, resonant waveguide grating biosensing and ELISA in the evaluation of a Dengue virus immunoassay”. D. Hu, S.R. Fry, J.X. Huang, X. Ding, L. Qiu, Y. Pan, Y. Chen, J. Jin, C. McElnea, J. Buechler, X. Che, & M.A. Cooper. Biosensors, 2013, 3, 297-311, DOI: 10.3390/bios3030297
  9. “A paramagnetic-reporter two-particle system for amplification-free detection of DNA in serum”. D.A.C. Thomson and M.A. Cooper. Biosensors and Bioelectronics. 2013, 50, 499-501,
  10. “The antigenic architecture of the hemagglutinin of influenza H5N1 viruses” T. Velkov, C. Ong, M.A. Baker, H. Kim, J. Li, R.L. Nation, J.X. Huang, M.A. Cooper and S. Rockman. Molecular Immunology, 2013, 56(4): 705-719.
  11. “Surface changes and polymyxin interactions with a resistant strain of Klebsiella pneumoniae” by T. Velkov, Z.Z. Deris, J. Huang, M. Azad, C. Dong, B. Boyd, M. Baker, M.A. Cooper, R. Nation, and J. Li. Innate Immunity, E-pub ahead of print 25 July 2013,
    DOI: 10.1177/1753425913493337
  12. “Molecular characterization of the receptor binding structure-activity relationships of influenza B virus hemagglutinin”, V. Carbone, H. Kim, J.X. Huang, M.A/ Baker, C. Ong, M.A. Cooper, J. Li, S. Rockman, T. Velkov. Acta virologica, 2013, 57(3): 313-352, DOI: 10.4149/av_2013_03_313
  13. “The Cytokine Release Inhibitory Drug CRID3 Targets ASC Oligomerisation in the NLRP3 and AIM2 Inflammasomes”, R.C. Coll, A.A.B. Robertson, M.S. Butler, M.A. Cooper, L.A.J. O'Neill, Plos One, 6(12): e29539. 2013, DOI: 10.1371/journal.pone.0029539
  14. "Antibacterial serrulatane diterpenes from the Australian native plant Eremophila microtheca”, E.C. Barnes, A.M. Kavanagh, S. Ramu, M.A. Blaskovich, M. A. Cooper, and R.A. Davis, Phytochemistry, 2013, 93, 162-169, DOI: 10.1016/j.phytochem.2013.02.021
  15. “Whole Genome Sequence Analysis of the First Australian OXA-48-Producing Outbreak-Associated Klebsiella pneumoniae Isolates: The Resistome and in vivo Evolution”, B. Espedido, J. Steen, H. Ziochos, S. Grimmond, M.A Cooper; I. Gosbell, S. van Hal, S. Jensen. Plos One, 2013, 8 (3) e59920, DOI: 10.1371/journal/pone.0059920
  16. “Efficient synthesis of anacardic acid analogues and their antibacterial activities”, S.K. Mamidyala, S. Ramu, J.X. Huang, A.B. Robertson, M.A. Cooper, Bioorg Med Chem Lett, 2013, 23 (6): 1667-670, DOI: 10.1016/j.bmcl.2013.01.074
  17. “Timed-release polymer nanoparticles”, T.D.T. Nguyen, N.P. Truong, W. Gu, Z. Jia,  M.A. Cooper, M.J. Monteiro, Biomacromolecules. 2013, 14(2), 495-502, DOI: 10.1021/bm301721k
  18. “Vancomycin: Ligand recognition, Dimerization and Super-complex Formation”, Z. Jia, M, O'Mara, J. Zuegg, M.A. Cooper, A. Mark, FEBS, 2013, 280 (5)1294-30, DOI: 10.1111/febs.12121
  19. “Molecular basis for the increased polymyxin susceptibility of Klebsiella pneumonia strains with under-acylated lipid A”, T. Velkov, R.L. Soon, P.L. Chong, J.X. Huang, M.A. Cooper, M.A.K. Azad, P.E. Thompson, K. Roberts, R.L. Nation, A. Clements, R.A. Strugnell & J. Li. Innate Immunity. 2013, 19(3): 265-77, DOI: 10.1177/1753425912459092



  1. "Aminoglycoside antibiotics in the 21st Century”, B. Becker, M.A. Cooper, ACS Chem Biol, 2012, 8(1), 105-115, DOI: 10.1021/cb3005116
  2. "Variation of the net charge, lipophilicity and side chain flexibility in Dmt1-DALDA: effect on opioid activity and biodistribution“ A. Novoa, S. Van Dorpe, E. Wynendaele, M. Spetea, N. Bracke, S. Stalmans, C. Betti, N. Chung, C. Lemieux, J. Zuegg, M. A. Cooper, D. Tourwé, B. De Spiegeleer, P. Schiller, S. Ballet, J. Med Chem, 2012, 55(22), 9549-61,
    DOI: 10.1021/jm3008079
  3. “Tumour-suppressor gene promoter hypermethylation in saliva of head and neck cancer patients” D.A. Ovchinnikov, M.A. Cooper, P. Pandit, W.B. Coman, J.J. Cooper-White, P. Keith, E.J. Wolvetang, P.D. Slowey & C. Punyadeera, Transl Oncol., 2012, 5(5):321-6,
    DOI: 10.1593/tlo.12232
  4. “Lipoamino acids as major components of absorption promoters in drug delivery”, Z.M. Ziora, M.A. Blaskovich, I. Toth & M.A. Cooper. Curr Topics in Med Chem, 2012, 12(14):1562-80, DOI: 10.2174/156802612802652448
  5. “Drug-Likeness and increased hydrophobicity of commercially available compound libraries for drug screening”, J. Zuegg & M.A. Cooper. Curr Topics Med Chem, 2012, 12(14), 1500-13, DOI: 10.2174/156802612802652466
  6. “Drug-binding energetics of human α-1-acid glycoprotein assessed by isothermal titration calorimetry”, T. Velkov, M.A.K. Azad, J.X. Huang, M.A. Cooper, N. M. Ching, R.L. Nation & J. Li. J. Mol. Recognit. 2012, 25(12), 642-56, DOI: 10.1002/jmr.2221
  7. “Identification of anti-tubercular benzothiazinone compounds by ligand-based design”, T. Karoli, B.Becker, J. Zuegg, U. Mollmann, S. Ramu, J.X. Huang & M.A. Cooper, J Med Chem, 2012, 55(17):7940-4, DOI: 10.1021/jm3008882
  8. “Resolving biofilm infections: Current therapy and drug discovery strategies”, M.V. Ranall, M.S. Butler, M.A. Blaskovich & M.A. Cooper. Curr. Drug Targets. 2012, 13(11), 1375-85,
    DOI: 10.2174/138945012803530251
  9. “A survey of the 2010 Quartz Crystal Microbalance literature”, R.E. Speight & M.A. Cooper. J Mol. Recognit., 2012, 25(9):451-73, DOI: 10.1002/jmr.2209
  10. “Molecular characterization of lipopolysaccharide binding to human α-1-acid glycoprotein”, J.X. Huang, M.A.K. Azad, R.L. Nation, J. Li, M.A. Cooper & T. Velkov. Journal of Lipids: Bacterial Lipids, 2012, 475153, DOI: 10.115/2012/475153
  11. “Development of anti-infectives using phase display: Biological agents against bacteria, viruses and parasites”, J.X. Huang, S.L. Bishop-Hurley, M.A. Cooper, Antimicrob Agents Ch, 2012, 56(9), 4569-82, DOI: 10.1128/AAC.00567-12
  12. “A comparative study of impedance versus optical label-free systems relative to labelled assays in a predominantly Gi coupled GPCR (C5aR) signalling”, R. Halai, D. Croker, J.Y. Suen, D.P. Fairlie & M.A. Cooper, Biosensors, 2012, 2, 273-290, DOI: 10.3390/bios2030273
  13. “Oligonucleotide and polymer functionalized nanoparticles for amplification-free detection of DNA”, D.A.C. Thomson, E.H-L. Tee, N.T.D. Tran, M.J. Monteiro & M.A. Cooper. Biomacromolecules. 2012, 13, 1981-1989, DOI: 10.1021/bm300717f
  14. “Structure-activity relationships for the binding of polymyxin antibiotics with human a-1-acid glycoprotein”. M.A.K. Azad, J.X. Huang, M.A. Cooper, K.D. Roberts, P.E. Thompson, J. Li, R.L. Nation, T. Velkov. Molecular Pharmaceutics, 2012, 84(3), 278-91,
    DOI: 10.1016/j.bcp.2012.05.004
  15. “Carriage of an ACME II Variant has contributed to MRSA ST239-like Strain Replacement in Liverpool Hospital, Sydney, Australia.” B. Espedido, J. Steen, T. Barbagiannakos, J. Mercer, D. Paterson, S. Grimmond, M.A. Cooper, I. Gosbell, S. vanHal & S. Jensen. Antimicrob Agents Ch. 2012, 56(6), 3380-3383, DOI: 10.1128/AAC.00013-12
  16. “The changing face of screening and drug discovery, Screening Asia 2011 Singapore: Conference Report.” M.A. Cooper. Exp. Rev. Proteomics, 2012, 9(2), 123-124,
    DOI: 10.1586/EPR.12.7
  17. "Structure aided design of chimeric antibiotics”, T. Karoli, S.K. Mamidyala, J. Zuegg, S.R. Fry, E.H-L. Tee, T.A. Bradford, P.K. Madala, J.X. Huang, S. Ramu, M.S. Butler & M.A. Cooper, Bioorganic & Medicinal Chemistry Letters, 2012  22, 2428-2433, DOI: 10.1016/j.bmcl.2012.02.019
  18. “Measurement of Drug Lipophilicity and pKa Using Acoustics”, X. Li & M.A. Cooper, Anal Chem. 2012 84(6), 2609-2613, DOI: 10.1021/ac300087z
  19. "Using label-free screening technology to improve efficiency in drug discovery”, R. Halai & M.A. Cooper, Expert Opinion on Drug Discovery, 2012, 7 (2), 123-131,
    DOI: 10.1517/17460441.2012.651121
  20. “Screening strategies to identify new antibiotics” M. S. Butler and M. A. Cooper, Current Drug Targets, 2012, 13(3), 373-387, DOI: 10.2174/138945012799424624

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  1. “The effect of environment on the recognition and binding of vancomycin to native and resistant forms of lipid II”,Z-G. Jia, M. O’Mara, J. Zuegg, M.A.Cooper & A. Mark, The Biophysical Journal, 2011, 101 (11), 2684-2692, DOI: 10.1016/j.bpj.2011.10.047
  2. “Fluorogenic pyrosequencing in microreactors”, J.A. Steen & M.A. Cooper, Nature Methods, 8 (7) July 2011, 548-549, DOI: 10.1038/nmeth.1634
  3. "Antibiotics in the clinical pipeline", M.S. Butler and M.A. Cooper, Journal of Antibiotics, 2011, 64, 413-425, DOI: 10.1038/ja.2011.44
  4. "The diagnostic sensitivity of dengue rapid test assays is significantly enhanced by using a combined antigen and antibody testing approach", S.R. Fry, M. Meyer, M.G. Semple, C.P. Simmons, S.D. Sekaran, J. X. Huang, C. McElnea, C-Y. Huang, A. Valks, P.R. Young and M.A. Cooper, PLoS NTD, 2011, 5 (6) 1-8, DOI: 10.1371/journal.pntd.0001199
  5. "Fix the antibiotic pipeline" M.A. Cooper & D.A. Shlaes, Nature, 7 April 2011 472, 32,
    DOI: 10.1038/472032a
  6. "Cyclizations using selenium chemistry for substituted 3-hydroxypiperidines and 3-hydryxopyrrolidines" M.A. Cooper and A. David Ward, Aust. J. Chem. 2011, 64, 1327-1338, DOI: 10.1071/CH11073
  7. "Biomarkers in Chronic Kidney Disease: a Review" R.G. Fassett, S.K. Venuthurupalli, G.C. Gobe, J.S. Coombes, M.A. Cooper and W. Hoy, Am. J. Kidney International. 2011, 80, 806-821, DOI: 10.1038/ki.2011.198
  8. “Separation and detection of bacteria using rupture event scanning” M.A. Cooper, F. N. Dultsev, V.P. Ostanin, D. Klenerman, Analytica Chimica Acta 2011, 702,233-238,
    DOI: 10.1016/j.aca.2011.06.025
  9. “A survey of the 2006-2009 quartz crystal microbalance biosensor literature”, M.A. Cooper and B. Becker, Journal of Molecular Recognition, 2011, 24, 754-787, DOI: 10.1002/jmr.1117
  10. "Amplification free detection of herpes simplex virus DNA from cerebrospinal fluid" D.A.C. Thomson, K. Dimitrov and M.A. Cooper, Analyst, 2011, 136 (8), 1599,
    DOI: 10.1039/c0an01021a
  11. "Membrane binding and perturbation studies of the antimicrobial peptides caerin, citropin, maculatin", B.C.S. Chia, Y. Gong, J.H. Bowie, J. Zuegg and M.A. Cooper, Biopolymers: Peptide Science, 2011, 96(2), 147-157, DOI: 10.1002/bip.21438



  1. “The synthesis of Essramycin and comparison of its antibacterial activity”, E. H-L. Tee, T. Karoli, S. Ramu, J.X. Huang, M.S. Butler and M. A. Cooper, Journal of Natural Products, 2010, 73 (11), 1940-1942, DOI: 10.1021/np100648q
  2. “Positive frequency shifts observed upon adsorbing micron-sized solid objects to a quartz crystal microbalance from the liquid phase”, A. Pomorska, D. Shchukin, R. Hammond, M.A. Cooper, G. Grundmeier, D. Johannsmann, Anal. Chem., 2010, 82 (6), 2237-2242,
    DOI: 10.1021/ac902012e
  3. “A signal amplification for HSV type 1 viral DNA detection using nanoparticles and direct acoustic profiling”, Y. Uludag, R. Hammond, M.A. Cooper, J. Nanobiotechnol., 2010, 8 (3),
    DOI: 10.1186/1477-3155-8-3, ISI Highly Accessed article
  4. “How to stress superbugs”, M.A. Cooper Australasian Sci., 2010, 31 (2), 31-32.
  5. “Vancomycin dimer formation between analogues of bacterial peptidoglycan surfaces probed by force spectroscopy”, M. Batchelor, D. Zhou, M.A. Cooper, C. Abell and T. Rayment Org. Biomol. Chem., 2010, 8, 1142-1148, DOI: 10.1039/b919347b



  1. “Bio-functionalized protein resistant oligo(ethylene glycol)-derived polymer brushes as selective immobilization and sensing platforms” J. Trmcic-Cvitas, E. Hasan, M. Ramstedt, X. Li, M.A. Cooper, C. Abell W.T.S. Huck and J.E. Gautrot, Biomacromolecules, 2009, 10 (10), 2885-2894, DOI: 10.1021/bm900706r
  2. “Signal transduction profiling using label-free biosensors”, M.A.Cooper, J. Recept. Signal. Transduct., 2009, 29 (3-4), 224-233, DOI:10.1186/1477-3155-8-3,
    DOI: 10.1080/10799890903047825
  3. “Resonant Acoustic Profiling for Diagnostics” M.A. Cooper SENSOR 2009 Proceedings, 2009, Vol. 1, 23-28, DOI: 10.5162/sensor09/v1/a1.1
  4. “Quantitative detection of Staphylococcal enterotoxin B by Resonant Acoustic Profiling”, M. Natesan, M.A. Cooper, J.P. Tran, V.R. Rivera, and M.A. Poli, Anal. Chem., 2009, 81 (10), 3896-3902, DOI: 10.1021/ac900086t


  1. “Resonant Acoustic Profiling for Biological Detection and Diagnostics” W. Chiu, C.J. Hammond, R. Hammond, L. Harding, E. Hawkins, X. Li, S. Moore, K. Sanders, A. Sleptsov, C. Zhou and M.A. Cooper, Proc. IEEE Intl. Freq. Control Symp., 2008, 350-355, DOI: 10.1109/FREQ.2008.4623018
  2. “Nanomechanical detection of antibiotic-mucopeptide binding in a model for superbug resistance”, J.W. Ndieyira, M. Watari, A.D. Barrera, D. Zhou, M. Vogtli, M. Batchelor, M.A. Cooper, T. Strunz, M.A. Horton, C. Abell, T. Rayment, G. Aeppli and R.A.McKendry, Nature Nanotechnol., 2008, 3 (11), 691-696, DOI: 10.1038/nnano.2008.275
  3. “A high sensitivity assay for the inflammatory market C-Reactive protein employing acoustic biosensing”, J.D. McBride and M.A. Cooper, J. Nanobiotechnol., 2008, 6 (5),
    DOI: 10.1186/1477-3155-6-5
  4. “Direct acoustic profiling of DNA hybridization using HSV viral sequences”, Y. Uludag, X. Li, H. Coleman, S. Efstathiou and M.A. Cooper, Analyst, 2008, 132, 52-57,
    DOI: 10.1039/b711850c
  5. “Single step biocompatible coating for sulfhydryl coupling of receptors via
    2-(pyridinyldithio)ethylcarbamoyl dextran”, X. Li, C. Abell, and M.A. Cooper, Colloid Interfac. Sci. B., 2008, 61, 113-117, DOI: 10.1016/j.colsurfb.2007.06.026


  1. “A survey of the 2001 to 2005 quartz crystal microbalance biosensor literature: applications of acoustic physics to the analysis of biomolecular interactions”, M.A. Cooper and V.T. Singleton, J. Mol. Recognit., 2007, 20 (3), 154-184, DOI: 10.1002/jmr.826
  2. “Piezoelectric sensors based on molecular imprinted polymers for quantitative detection of low molecular weight analytes”, Y. Uludağ, S.A. Piletsky, A.P.F. Turner and M.A. Cooper, FEBS, 2007, 274, 5471-5480, DOI: 10.1111/j.1742-4658.2007.06079.x
  3. “Profiling of molecular interactions in real time using acoustic detection”, B. Godber, M. Frogley, M. Rehak, A. Sleptsov, K.S.J. Thompson, Y. Uludag, and M.A. Cooper, Biosens. Bioelectron., 2007, 22 (9-10), 2382-2386, DOI: 10.1016/j.bios.2006.10.019


  1. “Acoustic detection technology in the analysis of biomolecular interactions”, E. Hawkins, M.A. Cooper and I. Campbell, Innovat. Pharm. Technol., 2006, 21, 30-34
  2. “Non-optical screening platforms: the next wave in label-free screening?”, M.A. Cooper, Drug Discov. Today, 2006, 11 (23/24), 1068-1074, DOI: 10.1016/j.drudis.2006.10.001
  3. “Quantification of small molecule-receptor affinities and kinetics by acoustic profiling”, X. Li, K.S.J. Thompson, B. Godber, and M.A. Cooper, Assay Drug Dev. Technol., 2006, 4 (5), 565-573, DOI: 10.1089/adt.2006.4.565
  4. “Current biosensor technologies in drug discovery”, M.A. Cooper, Drug Discov. World, 2006, 7 (3), 68-82
  5. “Real-time label-free acoustic technology for rapid detection of E. coli 0157:H7” L. Huang and M.A.Cooper, Clin. Chem, 2006, 52 (11), 2148-2151, DOI: 10.1373/clinchem.2006.072652
  6. “Optical biosensors; where next and how soon?”, M.A. Cooper, Drug Discov. Today, 2006, 11 (23/24), 1061-1067, DOI: 10.1016/j.drudis.2006.10.003

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  1. “Profiling molecular interactions using label-free acoustic screening”, M.A. Cooper and C.Whalen, Drug Discov. Today: Technologies., 2005, 2 (3), 241-245,
    DOI: 10.1016/j.ddtec.2005.08.014
  2. “Direct quantification of analyte concentration by Resonant Acoustic Profiling™ (RAP™)”, B. Godber, K.S.J. Thompson, M. Rehak, Y. Uludag, S. Kelling, A. Sleptsov, M. Frogley, K. Wiehler, C. Whalen and M.A. Cooper, Clin. Chem, 2005, 51 (10), 1962-1972,
    DOI: 10.1373/clinchem.2005.053249


  1. “The photodynamic therapy (PDT) anticancer activity of a range of porphyrin dimers and related compounds derived from hematoporphyrin”, C.J. Byrne, M.A. Cooper, P.A. Cowled, R.A.W. Johnstone, L. Mackenzie, L.V. Marshallsay, I.K. Morris, C.A. Muldoon, M.J.Raftery, S.S. Yin and A.D. Ward., Aust. J. Chem., 2004, 57, 1091-1102, DOI: 10.1071/CH04062
  2. “A biophysical characterisation of factors controlling dimerisation and selectivity in the NF-қB and NFAT families”, M. de Lumley, D.J. Hart, M.A. Cooper, S. Symeonides and J.M. Blackburn, J. Mol. Biol, 2004, 339 (5), 1059-1075, DOI: 10.1016/j.jmb.2004.03.083
  3. “Formation of dihydroxyselenides from allylic alcohols and their conversion to -hydroxy epoxides via substitution of a phenylselenonyl group.”, M.A. Cooper and A.D. Ward, Tetrahedron, 2004, 60 (36), 7963-7972, DOI: 10.1016/j.tet.2004.05.084
  4. “Advances in membrane receptor screening and analysis”, M.A. Cooper, J. Mol. Recognit., 2004, 17 (4), 286-315, DOI: 10.1002/jmr.675
  5. “A novel method of resistance for influenza against a channel-blocking anti-viral drug”, P. Astrahan, I. Kass, M.A. Cooper and I. T. Arkin, Proteins: Structure, Function, and Bioinformatics. 2004, 55 (2), 251-257, DOI: 10.1002/prot.20018



  1. “Design, synthesis, conformational analysis and nucleic acid hybridisation properties of thymidyl pyrrolidine-amide oligonucleotide mimics (POM)”, D.T. Hickman, T.H.S. Tan, J. Morral, P.M. King, M.A. Cooper and J. Micklefield, Org. Biomol. Chem. 2003, 1 (19), 3277-3292, DOI: 10.1039/b306156f
  2. “Biosensor profiling of molecular interactions in pharmacology”, M.A. Cooper, Curr. Op. Pharmacology, 2003, 3, 557-562, DOI: 10.1016/j.coph.2003.05.003
  3. “Label-free screening of bio-molecular interactions”, M.A. Cooper, Anal. Bioanal. Chem., 2003, 377 (5), 834-842, DOI: 10.1007/s00216-003-2111-y
  4. “Biosensing using rupture event scanning (REVS)”, M.A. Cooper, Meas. Sci. Technol., 2003, 14, 1888-1893, DOI: 10.1088/0957-0233/14/11/006
  5. “G-Quadruplex-Specific Peptide-Hemicyanine Ligands by Partial Combinatorial Selection”, J.A. Schouten, S. Ladame, S.J. Mason, M.A. Cooper and S. Balasubramanian, J. Am. Chem. Soc., 2003, 125, 5594- 5595, DOI: 10.1021/ja029356w
  6. “Binding of an inhibitor of the p53/MDM2 interaction to MDM2”, S.J. Duncan, M A. Cooper and D.H. Williams, J. Chem. Soc. Chem. Commun., 2003, (3), 316-317, DOI: 10.1039/b211889k


  1. “Sensitive and direct detection using Rupture Event Scanning (REVS)” S. Kelling, M.A. Cooper, K. Stirrups, R. Karamanska, V.P. Ostanin, D. Klenerman, A. Slepstov, M. Rehak, F.N. Dultsev, T. Minson and C. Abell, Proc. IEEE Intl. Freq. Control Symp., 2002, 756-760,
    DOI: 10.1109/FREQ.2002.1075982
  2. “Crystal structure of 2-(R*)-phenylselenomethyl-3(R*)-hydroxypyrrolidine-1-tosylate, C18H21NO3SSe”, M.A. Cooper, A.D. Ward and E.R.T. Tiekink, Z.Krist., 2002, 217, 343-344
  3. “Crystal structure of 2-(1-phenylselenonyl-1-phenylethoxy)ethanol, C16H18O4Se”, M.A. Cooper, A.D. Ward and E.R.T. Tiekink, Z.Kristallogr., 2002, 217, 345-346
  4. “A Sensitve and Economical Method to Directly Detect Particles”, M.A. Cooper, V.P. Ostanin, D. Klenerman, A. Slepstov, R. Karamanska, F.N. Dultsev, K. Stirrups, S. Kelling, T. Minson and C. Abell, Sensors 2002, Proceedings of IEEE, 2002, 2, 1042-1045
  5. “Optical Biosensors in Drug Discovery”, M.A. Cooper, Nature Rev. Drug Discov., 2002, 1, 515-528, DOI: 10.1038/nrd838
  6. “Mechanism of the regulation of type IB phosphoinositide 3OH-kinase by G protein subunits”, S. Krugmann, M.A. Cooper, D.H. Williams, P.T. Hawkins, and L.R. Stephens, Biochem. J., 2002, 362 (3), 725-731, DOI: 10.1042/bj3620725

  7. "Label-free screening of molecular interactions using acoustic detection", M.A. Cooper, Drug Discovery Today, 2002, 7 (5), S5-S7, DOI: 10.1007/s00216-003-2111-y
  8. "Acoustic detection of pathogens using rupture event scanning (REVS)", M.A. Cooper, Directions in Science, 2002, 1, 1-2, DOI: 10.1100/tsw.2002.68
  9. "Identification of ARAP3, a Novel PI3K Effector Regulating Both Arf and Rho GTPases, by Selective Capture on Phosphoinositide Affinity Matrices", S. Krugmann, K.E. Anderson, S.H. Ridley, N. Risso, A. McGregor, J. Coadwell, K. Davidson, A. Eguinoa, C.D. Ellson, P. Lipp, M. Manifava, N. Ktistakis, G. Painter, J.W. Thuring, M.A. Cooper, Z.-Y. Lim, A.B. Holmes, S.K. Dove, R.H. Michell, A. Grewal, A. Nazarian, H. Erdjument-Bromage, P. Tempst, L.R. Stephens and P.T. Hawkins, Mol. Cell, 2002, 9 (1), 95-108,
    DOI: 10.1016/S1097-2765(02)00434-3
  10. "The orientation of the antibiotic peptide maculatin 1.1 in DMPG and DMPC lipid bilayers. Support for a pore-forming mechanism", C.S.B. Chia, J. Torres, M.A. Cooper, I.T. Arkin and J.H. Bowie, FEBS Lett., 2002, 512 (1-5), 47-51, DOI: 10.1016/S0014-5793(01)03313-0



  1. "FENS-1 and FERG-1 are FYVE domain-containing proteins with distinct functions in the endosomal and Golgi compartments", S.H. Ridley, N. Ktistakis, K. Davidson, K.E. Anderson, M. Manifava, C.D. Ellson, P. Lipp, M. Bootman, J. Coadwell, A. Nazarian, H. Erjumont-Bromage, P. Tempst, M.A. Cooper, J.W.J.F. Thuring, z.-y. Lim, A.B. Holmes, L.R. Stephens and P.T. Hawkins, J. Cell. Sci, 2001, 114, 3991-4000
  2. "The synthesis of N-benzoyl aziridines from -benzamidoalkyl phenyl selenides", V.R. Ward, M.A. Cooper and A. D. Ward, Phophorus Sulfur Silicon and the Related Elements, 2001, 172 (1), 195-201, DOI: 10.1080/10426500108046651
  3. "Kinetically selective binding of single stranded RNA over DNA by a pyrrolidine–amide oligonucleotide mimic (POM)", D.T. Hickman, P.M. King, J.M. Slater, M.A. Cooper, and J. Micklefield, Nucleosides, Nucleotides & Nucleic Acids, 2001, 20 (4), 1169-1172, DOI: 10.1081/NCN-100002512
  4. “Direct and sensitive detection of a human virus by rupture event scanning”, M.A. Cooper, F.N. Dultsev, T. Minson, V.P. Ostanin, C. Abell, and D. Klenerman, Nature Biotech., 2001, 19, 833-837, DOI: 10.1038/news010906-1
  5. "Phosphatidylinositol 3-phosphate regulates the neutrophil oxidase complex by binding to the PX domain of p40phox ", C.D. Ellson, S. Gobert-Gosse, K.E. Anderson, K. Davidson, H. Erdjument-Bromage, P. Tempst, J.W. Thuring, M.A. Cooper, Z.-Y. Lim, A.B. Holmes, P.R.J. Gaffney, J. Coadwell, E.R. Chilvers, P.T. Hawkins and L.R. Stephens, Nature Cell Biol., 2001, 3, 679-682, DOI: 10.1038/35083076
  6. "Synthesis of N-acylaziridines from -amido selenides", V.R Ward, M.A. Cooper and A.D. Ward, J. Chem. Soc., Perkin Trans.I, 2001, 944-945, DOI: 10.1039/b102468j
  7. “Chemical force microscopy with active enzymes”, M. Fiorini, R. McKendry, M.A. Cooper, T. Rayment, and C. Abell, Biophys J., 2001, 80, 2471-2476, DOI: 10.1016/S0006-3495(01)76215-7
  8. “A convenient method for the aromatic amino-Claisen rearrangement of N-(1,1-disubstituted-allyl)anilines”, M.A. Cooper, M.A. Lucas, J.M. Taylor, A.D. Ward and N.M. Williamson, Synthesis, 2001, 4, 621-625, DOI: 10.1055/s-2001-12349


  1. "Unusual RNA & DNA binding properties of a novel pyrrolidine–amide oligonucleotide mimic (POM)", D.T. Hickman, P.M. King, M.A. Cooper, J.M. Slater and J. Micklefield, J. Chem. Soc. Chem. Commun., 2000, 2251-2252, DOI: 10.1039/b006903p
  2. “Binding of vancomycin group antibiotics to D-alanine and D-lactate presenting self-assembled monolayers”, M.A. Cooper, M.T. Fiorini, C. Abell, and D.H. Williams, Biorg. Med. Chem, 2000, 8, 2609-2616, DOI: 10.1016/S0968-0896(00)00184-X
  3. "The reactions of N-substituted-2-(2-dimethylallyl)aniline compounds with phenylselanyl halides", M.A. Cooper, C. L. Francis, J. W. Holman, B. Kasum, T. Taverner, E. R. T. Tiekink, and A. D. Ward, Aust. J. Chem, 2000, 53, 123-129, DOI: 10.1071/CH99109
  4. "Kinetic analysis of high-mobility-group proteins HMG1 and HMGI/Y binding to cholesteroltagged DNA on a supported lipid monolayer", C.I. Webster, M.A. Cooper, L.C. Packman, D.H. Williams, and J.C. Gray, Nucleic Acids Res., 2000, 28 (7), 1618-1624,
    DOI: 10.1093/nar/28.7.1618
  5. "A vesicle capture sensor chip for kinetic analysis of binding to membrane-bound receptors ", M.A. Cooper, A. Hansson, S. Löfas, S. and D.H. Williams, Anal. Biochem., 2000, 277, 196-205, DOI: 10.1006/abio.1999.4389


  1. "Binding of glycopeptide antibiotics to a model of a vancomycin-resistant bacterium", M.A. Cooper, and D. H. Williams, Chem. Biol., 1999, 6, 891-899, DOI:10.1016/S1074-5521(00)80008-3
  2. "Kinetic analysis of an antibody-antigen interaction on a supported lipid monolayer", M.A. Cooper, and D.H. Williams, Anal. Biochem, 1999, 276, 36-47, DOI: 10.1006/abio.1999.4333
  3. "High affinity surface binding of a strongly dimerising vancomycin group antibiotic to a model of resistant bacteria", D.P. O'Brien, R.M.H. Entress, M.A. Cooper, S.W. O'Brien, A. Hopkinson, and D.H. Williams, J. Am. Chem. Soc., 1999, 121, 5259-5265, DOI: 10.1021/ja9839769
  4. "Synthesis of extended bacterial cell-wall precursor analogues for ligand binding studies with glycopeptide antibiotics", T. Staroske, J. Görlitzer, R.M.H. Entress, M.A. Cooper and D.H. Williams, J. Chem. Soc., Perkin Trans. 1, 1999, 1105-1107, DOI: 10.1039/A809427F
  5. "The salt dependence of DNA recognition by NF-[kappa]B p50: a detailed kinetic analysis of the effects on affinity and specificity", D.J. Hart, R.E. Speight, M.A. Cooper, J.D. Sutherland, J.M. Blackburn, Nucleic Acids Res., 1999, 27 (4), 1063-1069, DOI: 10.1093/nar/27.4.1063


  1. "Surface Plasmon Resonance Analysis at a Supported Lipid Monolayer", M.A. Cooper, A.C. Try, J. Carroll, D.J. Ellar, D.H. Williams, Biophys. Biochim, Acta, 1998, 1373, 101-111, DOI: 10.1016/S0005-2736(98)00091-1
  2. "Bacillus thuringiensis Cry1Ac toxin interaction with Manduca sexta aminopeptidase N in a model membrane environment", M.A. Cooper, J. Carroll, E.R. Travis, D.H. Williams and D.J. Ellar, Biochem. J., 1998, 333, 677-683, DOI: 10.1042/bj33306779
  3. "19F NMR in the measurement of binding affinities of chloroeremomycin to model bacterial cell-wall surfaces which mimic VanA and VanB resistance", R.M.H. Entress, R.J. Dancer, D.P. O'Brien, A.C. Try, M.A. Cooper and D.H. Williams, Chem. Biol., 1998, 5, 329-337, DOI: 10.1016/S1074-5521(98)90171-5



  1. "The roles of dimerisation and membrane anchoring in activity of glycopeptide antibiotics against vancomycin-resistant bacteria", G. J. Sharman, A.C. Try, R.J. Dancer, Y.R. Cho, T. Staroske, B. Bardsley, A.J. Maguire, M.A. Cooper, D.P. O'Brien and D.H. Williams, J. Am. Chem. Soc, 1997, 119, 12041-12047, DOI: 10.1021/ja964477f
  2. "Surface plasmon resonance analysis of glycopeptide antibiotic activity at a model membrane surface", M.A. Cooper, D.H. Williams, and Y.R. Cho, J. Chem. Soc. Chem. Commun., 1997, 17, 1625-1626, DOI: 10.1039/a703943c
  3. “Synthesis and substitution reactions of N-protected-2-(phenylselenonylmethyl)-pyrrolidines”, M.A. Cooper and A. D. Ward, Aust. J. Chem., 1997, 50, 181-187, DOI: 10.1071/C96148



  1. "Crystal structure of ethyl 2-(phenylselenonylmethyl)pyrrolidine carboxylate", M.A. Cooper, E. R. T. Tiekink and A. D. Ward, Z.Krist., 1996, 211, 751-752,
    DOI: 10.1524/zkri.1996.211.10.751



  1. "Hydroxyselenation of allylic alcohols", M.A. Cooper and A. D. Ward, Tetrahedron Lett., 1995, 36 (13), 2327-2330, DOI: 10.1016/0040-4039(95)00247-A
  2. "Unusually stable hydrates of N-substituted 3-hydroxy-2 (phenylselenenyl)methylpiperidine derivatives. Where is the water? An NMR study", M.A. Cooper, S. M. Pyke, and A. D. Ward, Bull. Magn. Reson. 1995, 17 (1-4), 244-245



  1. "Selenium induced stereo-selective cyclization of N-substituted 4-hydroxy-5-hexenylamines", M.A. Cooper and A. D. Ward, Tetrahedron Lett., 1994, 35, 5065-5068, DOI: 10.1016/S0040-4039(00)73321-1



  1. "Selenium induced stereo-selective cyclizations of N-protected 3-hydroxy-4-pentenylamines", M.A. Cooper and A. D. Ward, Tetrahedron Lett., 1992, 33, 5999-6002, DOI: 10.1016/S0040-4039(00)61110-3


10 patent families with 19 international filings.

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